Controlled culture
A compact environmental control unit supports long-duration engineered-muscle maintenance.
Functional evidence, measured over time
Meet MyoReactor™
A research-use platform that cultures, stimulates, and repeatedly measures force in living engineered skeletal muscle—so one tissue can reveal maturation, response, injury, washout, and recovery.
DirectInline force sensing
RepeatedSame living tissue
IntegratedCulture through analysis
The missing endpoint
Cell survival is not muscle performance.
Viability, imaging, molecular markers, and terminal measurements each tell part of the story. Drug developers and researchers also need to know whether organized muscle can generate, sustain, and recover force—and how that function changes over time.
Conventional snapshots
- Separate tissues at each time point
- Proxy or destructive endpoints
- Limited view of onset and recovery
The MyoReactor approach
- Each tissue establishes its own baseline
- Direct passive, twitch, tetanic, and fatigue outputs
- Longitudinal response, washout, and recovery trajectories
Integrated platform
Built around living muscle function.
MyoReactor combines the physical environment, stimulation, measurement, and analysis required to move from engineered tissue to decision-relevant functional data.
Standardized chamber
A sterilizable chamber integrates tissue attachment, a fixed anchor, controlled media access, and sensor alignment.
Programmable stimulation
Integrated electrodes evoke reproducible twitch, tetanic, fatigue, and recovery responses.
Inline force sensing
Direct measurements are collected without transferring the tissue to a separate force bath.
Longitudinal design
The same construct is followed across maturation, exposure, injury, washout, and recovery.
Analysis software
Raw traces become passive tension, twitch, tetanic force, kinetics, fatigue, and recovery outputs.
One continuous experiment
From baseline to recovery.
A function-first workflow helps resolve not only whether an intervention changes muscle, but when the change begins, how it progresses, and whether the tissue recovers.
Fabricate
Form living 3D engineered muscle.
Mature
Maintain tissue under controlled conditions.
Baseline
Qualify each construct’s starting function.
Intervene
Apply a drug, toxicant, stressor, or genetic model.
Track
Measure progression, washout, and recovery.
Applications
Functional answers for muscle-focused decisions.
The initial commercial focus is research-use testing for pharmaceutical, biotechnology, CRO, toxicology, academic, and government teams.
Rx
Drug efficacy
Compare magnitude, onset, durability, fatigue response, and functional rescue.
Tx
Myotoxicity
Detect functional impairment that may precede overt cell death or visible damage.
DNA
Genetic models
Measure deficits and rescue across disease-associated or loss-of-function muscle models.
NMJ
Neuromuscular research
Support future studies of muscle–nerve interaction and functional response.
Δt
Aging, disuse & recovery
Resolve adaptation and recovery during long-duration physiological studies.
NAM
Human-relevant testing
Triage candidates and doses and refine later studies within validated contexts of use.
Development program
Advancing from prototype to beta-ready system.
SOMA’s program is designed to establish analytical performance, biological utility, model versatility, and a transferable external-user workflow.
Analytical performance
Establish sensitivity, accuracy, linearity, repeatability, inter-device reproducibility, temporal response, hysteresis, and drift.
Biological utility
Test an acute contraction enhancer, reversible inhibitor, and progressive myotoxicant against orthogonal endpoints.
Platform versatility
Demonstrate performance across human cell sources, iPSC or immortalized cells, and genetically altered muscle models.
SOMA team
Muscle biology meets product engineering.
The team combines decades of engineered-muscle physiology with hands-on development of the MyoReactor’s tissue, mechanical, and operational workflows.
Lisa M. Larkin, PhD
CEO / CSO / Founder & Inventor
Scientific direction, muscle physiology, intellectual property, partnerships, and platform roadmap.
Eileen Su
PD / PI & Program Leader
Program execution, integration, milestones, risk management, and product development.
Derek Hwang
Product Development Engineer
Mechanical design, chamber refinement, sensor alignment, calibration, and design for manufacture.
Measure what living muscle can do—not only what it contains.
MyoReactor is being developed to bring direct, longitudinal functional evidence into human engineered-muscle research.
Research-use platform in developmentNot intended for clinical diagnosis or treatment. Application-specific evidence will define appropriate contexts of use.